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Cooper GM. The Cell: A Molecular Approach. 2nd edition. Sunderland (MA): Sinauer Associates; 2000.

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The Cell: A Molecular Approach. 2nd edition.

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Figure 13.19. Regulation of protein kinase A.

Figure 13.19Regulation of protein kinase A

The inactive form of protein kinase A consists of two regulatory (R) and two catalytic (C) subunits. Binding of cAMP to the regulatory subunits induces a conformational change that leads to dissociation of the catalytic subunits, which are then enzymatically active.


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