Fig. 17.59. Plasma cell myeloma.

Fig. 17.59

Plasma cell myeloma. Regressing marrow elements with pyknosis of megakaryocytes that are surrounded by cells with massive amounts of quite densely eosinophilic cytoplasm. The nuclei are moderately hyperchromatic and round to oval with moderate anisokaryosis and frequent binucleation. The chromatin pattern is a vesiculated counterpart of plasmacytoma with large chromocenters that are more widely separated by irregular areas of pale-staining parachromatin and generally without clear areas. Many of the nuclei contain one to two nucleoli, and mitotic index in the tumor population tends to be very low. Bar = 30 microns.*)

From: Chapter 17, TUMORS OF HEMATOPOIETIC AND LYMPHOID TISSUES

Cover of Comparative Oncology
Comparative Oncology.
Baba AI, Câtoi C.
Copyright © 2007, The Publishing House of the Romanian Academy.

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