TABLE 16.1

TRP Channels Regulated by Osmomechanical Stresses

SpeciesTRP ChannelFamily SubtypeActivation by Osmo- and Mechanical Stresses
Caenorhabditis elegans   
 OSM-9TRPVOsmolality (hyper), touch
 OCR-2TRPVOsmolality (hyper), touch
 NOMPCTRPNStretch
Drosophila   
 NANTRPVOsmolality (hypo), stretch
 IAVTRPVOsmolality (hypo), stretch
Mammals   
 TRPV1TRPVOsmolality (hyper), stretch
 TRPV2TRPVOsmolality (hypo), stretch, shear stress
 TRPV4TRPVOsmolality (hypo), shear stress
 TRPC1TRPCOsmolality (hypo), stretch
 TRPC6TRPCStretch
 TRPP2TRPPOsmolality (hypo), stretch
 TRPP3TRPPOsmolality (hypo)
 TRPA1TRPAStretch
 TRPM3TRPMOsmolality (hypo)
 TRPM4TRPMStretch
 TRPM7TRPMOsmolality (hypo), stretch, shear stress

From: Chapter 16, Regulation of TRP Channels by Osmomechanical Stress

Cover of TRP Channels
TRP Channels.
Zhu MX, editor.
Boca Raton (FL): CRC Press/Taylor & Francis; 2011.
Copyright © 2011 by Taylor and Francis Group, LLC.

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