Table 15Strength of evidence for ADHD and disruptive behavior disorders (Key Question 3)

ComparisonOutcome (N Studies; N Patients)Strength of Evidence DomainsStrength of Evidence
ROBConsistencyDirectPrecision
SGA vs. placeboHRQL (1; 19)ModerateUnknownDirectPreciseInsufficient
Medication adherence (5; 311)ModerateInconsistentDirectImpreciseLow

ADHD = attention deficit hyperactivity disorder; HRQL = health-related quality of life; N = number; ROB = risk of bias; SGA = second-generation antipsychotic

From: Results

Cover of First- and Second-Generation Antipsychotics for Children and Young Adults
First- and Second-Generation Antipsychotics for Children and Young Adults [Internet].
Comparative Effectiveness Reviews, No. 39.
Seida JC, Schouten JR, Mousavi SS, et al.

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