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Cover of The Science and Applications of Synthetic and Systems Biology

The Science and Applications of Synthetic and Systems Biology

Workshop Summary

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Washington (DC): National Academies Press (US); .
ISBN-13: 978-0-309-21939-6ISBN-10: 0-309-21939-6

Excerpt

Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine’s (IOM’s) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. Through invited presentations and discussion, participants explored the ways in which synthetic and systems biology are contributing to drug discovery, development, and production; vaccine design and development; and infectious disease detection and diagnostics. In addition, workshop participants considered how synthetic biology could be used to engineer, or reengineer, microbial host cells to detect environmental toxins, produce carbon-neutral fuels, and produce novel raw materials.

Contents

Rapporteurs: Eileen R. Choffnes, David A. Relman, and Leslie Pray

Financial support for this project was provided by the U.S. Department of Health and Human Services: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Centers for Disease Control and Prevention, Food and Drug Administration, and the Fogarty International Center; U.S. Department of Defense, Department of the Army: Global Emerging Infections Surveillance and Response System, Medical Research and Materiel Command, and the Defense Threat Reduction Agency; U.S. Department of Veterans Affairs; U.S. Department of Homeland Security; U.S. Agency for International Development; American Society for Microbiology; sanofi pasteur; Burroughs Wellcome Fund; Pfizer, Inc.; GlaxoSmithKline; Infectious Diseases Society of America; and the Merck Company Foundation.

Suggested citation:

IOM (Institute of Medicine). 2011. The Science and Applications of Synthetic and Systems Biology. Washington, DC: The National Academies Press.

Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the view of the organizations or agencies that provided support for this project.

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine.

Copyright © 2011, National Academy of Sciences.
Bookshelf ID: NBK84445PMID: 22497031
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