Slide 17. The Pickhardt Study -Statistical Analysis.

Slide 17The Pickhardt Study -Statistical Analysis

SLIDE 17 NOTES: The Pickhardt study employed segmental unblinding, which means that as the colonoscope passes through a segment, any indication from the VC results that a lesion may have been missed would lead to re-examination of that segment of the colon to attempt to verify its existence.

Polyps were matched between VC and OC by a finding of polyp in the same or adjacent segment with diameters that were within 50 percent of one another.

All polyps found on optical colonoscopy were resected and sent for pathology.

Procedure times were recorded, and questionnaires were provided to patients.

The reference standard for a true positive was the segmentally unblinded optical colonoscopy result.

From: Appendix J, Recent Findings on Test Performance

Cover of Economic Models of Colorectal Cancer Screening in Average-Risk Adults
Economic Models of Colorectal Cancer Screening in Average-Risk Adults: Workshop Summary.
Institute of Medicine (US); National Research Council (US); Pignone M, Russell L, Wagner J, editors.
Washington (DC): National Academies Press (US); 2005.
Copyright © 2005, National Academy of Sciences.

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