Figure 4. Simultaneous stretching of a guinea pig ventricular myocyte and recording of electrical activity.

Figure 4

Simultaneous stretching of a guinea pig ventricular myocyte and recording of electrical activity. The microelectrode is used to record membrane potential or currents. It is placed behind the stiff fibre to protect the site of impalement during stretch. The supple fibre is used to stretch the cell and its displacement during stimulation gives a measure of active force development (increased resting force caused by the stretch cannot be measured in this configuration). Increased sarcomeric spacing is used as the index of stretch. Experiments were performed at 37°C. From Belus & White [10].

From: Mechanical Modulation of Intracellular Ion Concentrations: Mechanisms and Electrical Consequences

Cover of Mechanosensitivity in Cells and Tissues
Mechanosensitivity in Cells and Tissues.
Kamkin A, Kiseleva I, editors.
Moscow: Academia; 2005.
Copyright © 2005, Academia Publishing House Ltd.

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