Figure 4. Changes in membrane potential during a membrane stretch with different conductance of SACs in a model simulation.

Figure 4

Changes in membrane potential during a membrane stretch with different conductance of SACs in a model simulation. The stretch channel conductance is 10 (a), 15 (b), 20 (c), 25 (d) μS/μF, respectively. The degree of diastolic depolarization is dependent on the conductance of SACs. When the diastolic depolarization reaches a threshold, an action potential is fired without electrical stimulus.

From: Role of Stretch-activated Channels in the Heart: Action Potential and Ca2+ Transients

Cover of Mechanosensitivity in Cells and Tissues
Mechanosensitivity in Cells and Tissues.
Kamkin A, Kiseleva I, editors.
Moscow: Academia; 2005.
Copyright © 2005, Academia Publishing House Ltd.

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