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This volume is based on the diagnosis of epilepsy. A primary difficulty in diagnosing epilepsy is the variability of epileptic seizure types. Although stereotyped in a given patient, even epileptic seizures identified as arising from the same brain area may have different semiologies in different patients. Epileptic seizures may present with such disparate features as formed visual hallucinations or tingling in the left hand. Nonetheless, epileptic phenomena typically fall into recognizable clinical patterns. As many have noted, the "border lands" of epilepsy cover a vast, poorly charted territory. Imitators of Epilepsy will have been successful if it serves to increase the awareness of physicians for factors that distinguish epileptic seizures from their imitators, and to provide guidance to support clinical judgment in approaching patients with possible seizure disorders.
Contents
- Dedication
- Preface
- Acknowledgments
- Contributors
- Introduction Approach to the Diagnosis of Possible Seizures
- Chapter 1. Electroencephalography in the Diagnosis of Nonepileptic and Epileptic ConditionsWarren T. Blume, MD, FRCP(C)
- EEG and the Diagnosis of Epilepsy
- EEG in Some Epilepsy Mimics
- EEG in Evaluation of Ambiguous Disorders: Various Practical Points
- References
- Chapter 2. Anatomical–Clinical Localization of Ictal BehaviorBarbara Jobst, MD and Peter Williamson, MD.
- Manifestations and Localization of Ictal Behavior in Focal Partial Seizures
- Ictal Behavior Originating in the Temporal Lobes
- Typical Seizures Originating in the Temporal Lobes
- Ictal Behavior Originating in the Parietal Lobes
- Ictal Behavior Originating in the Occipital Lobe
- Seizures Originating in the Deeper Structures of the Brain
- Conclusion
- References
- Chapter 3. Curious Epileptic Seizures That Don't Resemble SeizuresMonisha Goyal, MD, Paul Zarkowski, MD, and Barbara E. Swartz, MD, PhD.
- Seizures That Don'T Resemble Seizures in Neonates
- Seizures That Don'T Resemble Seizures in Infants
- Seizures That Don'T Resemble Seizures in Older Children and Adults (1.0 Motor)
- Reflex Epilepsies
- Psychic Seizures
- Seizures with Psychiatric Symptomatology
- Conclusion
- References
- Chapter 4. Convulsive Nonepileptic SeizuresDon W. King, MD.
- Convulsive Epileptic Seizures
- Convulsive Syncope
- Psychogenic Nonepileptic Events
- Paroxysmal Dyskinesia
- Periodic Limb Movements of Sleep
- REM Behavior Disorder
- References
- Chapter 5. The Role of Serum Prolactin in Seizure DiagnosisPaul B. Pritchard, III, MD.
- Effects of Drugs on Serum Prolactin Levels
- Changes in Serum Prolactin Levels with Pathologic States
- Changes in Serum Prolactin with Brain Stimulation
- Changes in Serum Prolactin Associated with Epileptic Seizures
- Psychogenic Nonepileptic Seizures
- Other Paroxysmal Neurological Conditions
- Use of Serum Prolactin as a Diagnostic Tool in Epilepsy: Practice and Pitfalls
- References
- Chapter 6. Nonepileptic Spells in Neonates and InfantsLinda Laux, MD and Douglas R. Nordli, Jr, MD.
- Neonates (Birth to One Month of Age)
- Neonatal Nonepileptic Events
- Infants (One Month to One Year of Age)
- Conclusion
- References
- Chapter 7. Nonepileptic Seizures and Similar Phenomena in Children and AdolescentsJohn B.P Stephenson, MA, BM, DM, FRCP, HonFRCPCH and Sameer Zuberi, MB, ChB, MRCPCH, FRCP.
- Nonepileptic Seizures and Paroxysmal Nonepileptic Events in the Population
- Classification of Nonepileptic Seizures and Events
- Diagnostic Categories
- Conclusion
- References
- Chapter 8. Paroxysmal Disturbances Resembling Seizures in the ElderlyA. James Rowan, MD.
- The Aged Person Found Unconsciousness on the Floor
- Blackout Spells
- Drop Attacks
- Syncope
- Memory Disturbances
- Dementia
- Dizziness
- Transient Ischemic Attacks
- Transient Global Amnesia
- Tremor and Clonus
- Myoclonic Jerks
- Toxic-Metabolic Encephalopathies
- Nonconvulsive Status Epilepticus
- References
- Chapter 9. Migraine and EpilepsyAudrey L. Halpern, MD and Stephen D. Silberstein, MD.
- The Migraine Attack—A Clinical Description
- Migraine Variants
- Headache and Seizure Occur Together
- Migraine-Triggered Epilepsy
- Pathophysiology of Migraine
- The EEG and Migraine
- Pharmacologic Treatment of Migraine—Basic Principles
- Neuropharmacology of Migraine Treatment
- Some Diagnostic Distinctions among Migraine, Epileptic Seizures and Transient Global Amnesia
- References
- Chapter 10. Strange Tastes, Smells, Sounds, Visions and Feelings: Nonepileptic Events that Mimic Simple Partial SeizuresRoss FineSmith, MD, Eric B. Geller, MD, and Orrin Devinsky, MD.
- Nonepileptic Paroxysmal Disorders
- Simple Partial Epileptic Seizures and Their Nonepileptic Imitators
- Conclusion
- References
- Chapter 11. Dizziness or Vestibular Problems Resembling SeizuresMartin Gizzi, MD, PhD and Sidney P. Diamond, MD.
- Anatomy and Physiology of the Vestibular System
- The Clinical History
- The Neurotologic Examination—Key Elements
- Features Suggesting Otologic Causes of Vertigo
- Testing of Value in Vertigo
- Vertiginous Seizures
- Nystagmus in Epilepsy
- Vestibulogenic Seizures
- Features Suggesting Seizure as the Cause of Vertigo
- Conclusion
- References
- Chapter 12. Movement Disorders That Imitate EpilepsyAnn Helms, MD and Lisa Shulman, MD.
- Post-Stroke Epilepsy
- Post-Stroke Movement Disorders
- Chorea, Athetosis, and Ballismus
- Dystonia
- Muscle Cramps and Spasms
- Myoclonus
- Paroxysmal Dyskinesia
- Psychogenic Movement Disorders
- Tardive Dyskinesia
- Tardive Dystonia
- Tics
- Stereotypies
- Hemifacial Spasm
- Blepharospasm and Meige's Syndrome
- References
- Chapter 13. Hyperekplexia and Other Disorders of Startle: Differential Diagnosis with EpilepsyFrederick Andermann, MD, FRCP(C) and Eva Andermann, MD, PhD, FCCMG.
- Hyperekplexia
- Startle Epilepsy
- Jumping and Other Culture-Bound Syndromes
- References
- Chapter 14. Encephalopathy as a Mimic of SeizuresMichael Benatar, MBChB, Dphil and Frank W. Drislane, MD.
- The Anatomy and Physiology of Arousal
- Pathophysiology of Encephalopathy
- The Clinical Features of Encephalopathy
- Electroencephalographic Features of Encephalopathy
- Seizures and Related Disorders That Produce an Encephalopathy
- Similarities and Differences between Encephalopathy and Ncse
- Conclusion
- References
- Chapter 15. Neuroendocrine, Metabolic and Toxic Imitators of EpilepsyRobin L. Gilmore.
- Introduction
- Gastrointestinal Disease and Seizures
- Toxic or Drug-Related Conditions
- MDMA
- Vasculitic Encephalopathies
- References
- Chapter 16. Parasomnias, Sleep Disorders, and Narcolepsy—Sleep-Time Imitators of EpilepsyCarl W. Bazil, MD, PhD.
- Normal Sleep Physiology
- Interactions between Sleep and Epilepsy
- Specific Sleep Phenomena and Sleep Disorders Confused with Seizures
- Diagnostic and Treatment Strategies
- Conclusion
- References
- Chapter 17. Cerebrovascular Imitators of EpilepsyLouis R. Caplan, MD.
- Clinical Features Used to Separate Seizures, Transient Ischemia, and Migraine
- Less Common Mimics Attributed to, or Confused with Cerebrovascular Disease
- References
- Chapter 18. Hyperventilation SyndromeRandolph W. Evans, MD.
- Epidemiology
- Historical Aspects
- Diagnosis
- Neurologic Manifestations
- Psychologic Symptoms
- Case Reports
- Pathophysiology
- Differential Diagnosis
- Treatment
- Prognosis
- References
- Chapter 19. Psychiatric Aspects of Nonepileptic Seizures: Psychogenic NESJohn R. Gates, MD.
- Terminology
- Epidemiology
- Diagnosis and Treatment
- Video-EEG Monitoring
- Neuropsychological Testing
- Treatment of Nonepileptic Seizures
- Conclusion
- References
- Chapter 20. Coexisting Epilepsy and Nonepileptic SeizuresAllan Krumholz, MD and Tricia Ting, MD.
- History
- Definitions
- Epidemiology
- Provoking Factors
- Diagnosis
- Epileptic Seizures Mimicking Nonepileptic Seizures
- Treatment
- Prognosis
- References
- Chapter 21. Panic Attacks and Panic Disorders: The Great ImitatorsMeghan M. Grady, BA and Stephen M. Stahl, PhD, MD.
- Panic Attacks
- Panic Disorder
- Agoraphobia
- Etiologies
- Differential Diagnosis
- Treatment
- Prognosis
- References
- Imitators of EpilepsyImitators of EpilepsyBookself
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