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Jonas DE, Wines RCM, DelMonte M, et al. Drug Class Review: Controller Medications for Asthma: Final Update 1 Report [Internet]. Portland (OR): Oregon Health & Science University; 2011 Apr.

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Drug Class Review: Controller Medications for Asthma: Final Update 1 Report [Internet].

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Final Update 1 Evidence Tables B

Evidence Table 1. Trials key questions 1 and 2 (MS Excel, 57K)

Evidence Table 2. Internal validity: Trials key question 1 (MS Excel, 28K)

Evidence Table 3. Internal Validity: Trials key question 2 (MS Excel, 17K)

Evidence Table 4. Systematic Reviews: Key questions 1 and 2 (MS Excel, 29K)

Evidence Table 5. Internal Validity: Systematic reviews key questions 1 and 2 (MS Excel, 11K)

Evidence Table 6. Observational studies key questions 2 and 3 (MS Excel, 14K)

Evidence Table 7. Internal Validity: Observational studies key questions 2 and 3 (MS Excel, 11K)

Abbreviations used in evidence tables

ACT

Active-control trial

AD

adjustable dosing

AE

Adverse event

ANCOVA

Analysis of covariance

ANOVA

Analysis of variance

AQLQ

Asthma Quality of Life Questionnaire

ARF

Arformoterol

BDP

beclomethasone dipropionate

bid

Twice daily

BIS

Budesonide inhalation suspension

BMI

Body mass index

BUD

Budesonide

BUD/FM

budesonide and formoterol in one inhaler

BUD+FM

budesonide and formoterol in separate inhalers

CCT

Controlled clinical trial

CI

Confidence interval

CIC

Ciclesonide

CNS

Central nervous system

CR

Controlled release

CV

Cardiovascular

CVS

Cardiovascular system

d

Day

DB

Double-blind

DD

double dummy

dL

Deciliter

DPI

dry powder inhaler

ECG

Electrocardiogram

EEG

Electroencephalogram

EF

Ejection fraction

eFM

Eformoterol

ER

Extended release

FD

fixed dose

FDA

US Food and Drug Administration

FLUN

Flunisolide

FM

Formoterol

FP

Fluticasone Propionate

FP/SM

fluticasone and salmeterol in one inhaler

FP+SM

fluticasone and salmeterol in separate inhalers

FrACQ

French version of the Juniper Asthma Control Questionnaire

FU

Follow-up

g

Gram

GI

Gastrointestinal

GP

General practitioner

GPRD

general practice research database

h

Hour

HDL-C

High density lipoprotein cholesterol

HFA

hydrofluoroalkane propellant

HMO

Health maintenance organization

HR

Hazard ratio

HRQOL

Health-related quality of life

ICD-10

International Classification of Diseases, Tenth Revision

ICD-9

International Classification of Diseases, Ninth Revision

ICS

Inhaled Corticosteroids

IOP

intraocular pressure

IR

Immediate release

ITT

Intention-to-treat

L

Liter

LA

Long acting

LABAs

Long-Acting Beta-2 Agonists

LDL-C

Low-density lipoprotein cholesterol

LM

Leukotriene Modifiers

LOCF

Last Observation Carried Forward

LS means

Least squares means

LTRAs

Leukotriene receptor antagonists

MA

meta-analysis

MANCOVA

Multivariate analysis of covariance

mcg

Microgram

MDI

metered dose inhaler

mg

Milligram

min

Minute

ML

Montelukast

mL

Milliliter

mo

Month

MOM

Mometasone

N

Sample size (entire sample)

n

Subgroup sample size

NA

Not applicable

NNT

number needed to treat

NNT(h)

number needed to treat/harm

NR

Not reported

NS

Not significant

NSD

No significant difference

OCS

oral corticosteroids

OM

Omalizumab

OR

Odds ratio

P

P value

P

Placebo

PAQLQ

Pediatric Asthma Quality of Life Questionnaire

PAR

persistent allergic rhinitis

PCT

Placebo-controlled trial

pMDI

pressurized metered dose inhaler

PPY

Per person year

PSC

posterior subcapsular cataracts

qd

Once daily

QOL

Quality of life

RAMQ

regi de l’assurance maladie du Quebec database

RCT

randomized controlled trial

RCT

Randomized controlled trial

RQLQ

Rhinitis Quality of Life Questionnaire

RR

Relative risk

SABA

Short-Acting Beta-Agonist

SB

Single-blind

SD

Standard deviation

SE

Standard error

SM

Salmeterol

SMD

standard mean difference

SPT

skin prick test

SR

systematic review

TAA

Triamcinolone Acetonide

tid

Three times daily

VAS

Visual analog scale

vs.

Compared with (versus)

WD

Withdrawal

XR

Extended release

y

Year

ZAF

Zafirlukast

Copyright © 2011 by Oregon Health & Science University.
Bookshelf ID: NBK66161
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