Table 2. Definitions of TNM Stage I

StageTNMa,bDukescMACdDescriptionIllustration
IT1, N0, M0AAT1 = Tumor invades submucosa.
Stage I colorectal cancer; shows a cross-section of the colon/rectum. An inset shows the layers of the colon/rectum wall with cancer in the mucosa, submucosa, and muscle layers. Also shown are the serosa, a blood vessel, and lymph nodes.
T2 = Tumor invades muscularis propria.
N0 = No regional lymph node metastasis.
T2, N0, M0AB1M0 = No distant metastasis.

T = primary tumor; N = regional lymph nodes; M = distant metastasis.

Reprinted with permission from AJCC: Colon and rectum. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 143-164.

The explanations for superscripts a–g are at the end of Table 5.

From: Colon Cancer Treatment (PDQ®)

Cover of PDQ Cancer Information Summaries
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.

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