Figure 5. The I-TevI zinc finger acts as a distance determinant.

Figure 5

The I-TevI zinc finger acts as a distance determinant. The two different scenarios for cleavage preference of wild-type I-TevI at distance (top), and the zinc-finger mutant at sequence (bottom), are presented. Scissors represent site of preferred cleavage as described in the text. Linker organizer (A) and catalytic clamp (B) models for distance determination are designated on the wild-type protein, in the top panel.

From: Homing Endonuclease I-TevI: An Atypical Zinc Finger with a Novel Function

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