Figure 1. Overview of three-dimensional structural information currently available for I-TevI.

Figure 1

Overview of three-dimensional structural information currently available for I-TevI. The enzyme consists of an N-terminal catalytic domain joined to the C-terminal DNA-binding domain by a long, flexible linker that remains to be structurally characterized. The DNA-binding domain itself has an elongated structure and could only be crystallized in the presence of its DNA substrate.

From: Homing Endonuclease I-TevI: An Atypical Zinc Finger with a Novel Function

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