Figure 9. Changes in the phenotype of lymphocytes recovered from M40403 treated LAK cultures.

Figure 9

Changes in the phenotype of lymphocytes recovered from M40403 treated LAK cultures. Flow cytometric analysis of lymphocyte subsets derived from splenocytes (106/ml) incubated with 6000 IU IL-2/ml for 3 days with or without 10 μM M40403 (expressed as absolute cell recovery, mean ± SD). NK-1 and peanut lectin (PNA, recognizes asialo-GM-1 glycan structure) are markers for NK subsets, while Mac-1 (CD11b) is a macrophage marker.

From: Evaluation of a Superoxide Dismutase Mimetic As an Adjunct to Interleukin 2 Based Cancer Therapy

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