Figure 2. Proteins encoded by polyomavirus BKV, JCV and SV40 share amino acid sequence homologies.
Figure 2. Proteins encoded by polyomavirus BKV, JCV and SV40 share amino acid sequence homologies.

Figure 2

Proteins encoded by polyomavirus BKV, JCV and SV40 share amino acid sequence homologies. Alignment of the primary amino acid sequence of the structural proteins VP1, VP2, VP3, the agnoprotein, and the functional proteins large T- and small t-antigen of BKV (Dunlop), JCV (CY), and SV40 (strain 766) identify high degree of homology regions with impact on serological crossreactions and thereby on seroepidemiology of the individual polyomavirus strains. Identical amino acids are shown in black, while different amino acids are gray (shown in red in online version). Arrow indicates start of the VP3 sequence.

From: Immunity and Autoimmunity Induced by Polyomaviruses: Clinical, Experimental and Theoretical Aspects

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