ClinicalThere were no studies which reported the number of patients with visual field progression.
There is no statistically significant difference between a separate combination of prostaglandin analogues + beta-blockers and prostaglandin analogues alone in reducing IOP from baseline at 6 months follow up. (VERY LOW QUALITY)
There is no statistically significant difference between a separate combination of prostaglandin analogues + beta-blockers and prostaglandin analogues alone in increasing the number of patients with an IOP of approx <18 mmHg at 6 months follow up. (LOW QUALITY)
There is no statistically significant difference between a separate combination of prostaglandin analogues + beta-blockers and prostaglandin analogues alone in the number of patients experiencing a respiratory adverse event at 6 months follow up. (VERY LOW QUALITY)
There is no statistically significant difference between a separate combination of prostaglandin analogues + beta-blockers and prostaglandin analogues alone in the number of patients experiencing hyperaemia at 6 months follow up. (VERY LOW QUALITY)
EconomicSeparate combinations of prostaglandin analogues plus beta-blockers are more effective (not statistically significant) but more costly than prostaglandin analogues alone. This evidence has serious limitations and partial applicability.

From: 8, Treatment of chronic open angle glaucoma

Cover of Glaucoma
Glaucoma: Diagnosis and Management of Chronic Open Angle Glaucoma and Ocular Hypertension.
NICE Clinical Guidelines, No. 85.
National Collaborating Centre for Acute Care (UK).
Copyright © 2009, National Collaborating Centre for Acute Care.

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