Figure 5. Schematic representation of network growth through gene duplication.

Figure 5

Schematic representation of network growth through gene duplication. A) shows pure gene duplication where a new node is created by duplicating the connectivity of the parent. This results in an increase in degree of the neighboring nodes. Node i is duplicated to give i '. Nodes j, k, l are neighbors. B) the partial duplication model where node i is duplicated to i' but not all the original connections are retained. C) shows a rewiring process where edge i-j is rewired to become i-k. Reprinted with permission from Bhan A, Galas DJ, Dewey TG Bioinformatics 2002;18:1486-1493.

From: Gene Regulatory Networks

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