Figure 2. Processing and maturation of a tmRNA precursor.

Figure 2

Processing and maturation of a tmRNA precursor. Both the 5' and the 3' ends are processed. Two post-transcriptional modifications are added to the mature form, probably via a tRNA-specific methyl transferase and a pseudouridine synthase. In one tmRNA sequence, Clostridium botulinum, a group I intron interrupts the tmRNA T-loop, and is proposed to be spliced in vivo.

From: Protein Tagging and Ribosome Rescue in Bacteria Requires the Recognition of Transfer-Messenger RNA by an Aminoacyl-tRNA Synthetase

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