Figure 3. A putative nucleosome structure formed on the poly(dA•dT)-containing wild-type AMT1 promoter (left).

Figure 3

A putative nucleosome structure formed on the poly(dA•dT)-containing wild-type AMT1 promoter (left). Also shown is a putative nucleosome structure formed on a mutant promoter (right), which carried “normal” DNA instead of the poly(dA•dT) sequence. A16: the (dA•dT)16 tract; S16 (“normal” DNA): a random sequence predicted to assume a B-form DNA structure; AMT1: Amt1-binding site. In the wild-type, compared to the mutant, the Amt1-binding site is more accessible owing to the adjacent homopolymeric (dA•dT) tract. Reproduced from ref. 17 with permission from Elsevier (©1996).

From: The Role of Unusual DNA Structures in Chromatin Organization for Transcription

Cover of Madame Curie Bioscience Database
Madame Curie Bioscience Database [Internet].
Austin (TX): Landes Bioscience; 2000-.
Copyright © 2000-2013, Landes Bioscience.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.