Figure 2. Epithelial appendages can regrow after epithelia and mesenchyme are separated and recombined.

Figure 2

Epithelial appendages can regrow after epithelia and mesenchyme are separated and recombined. This shows the process that is common to all epithelial appendages. First a series of interactions takes place between the epithelia (E) and mesenchyme (M). In the early stages of morphogenesis, phenotypes are still flexible. Gradually, they become irreversibly committed (as represented by the increasing size of arrows). Cross recombination between two types of epithelial appendages (E1, E2) shows that the mesenchyme (M1, M2) has more control over the phenotypes of epithelial appendages, but epithelia can only respond within their competence at the time that stimuli are given. See color insert.

From: Morphogenesis of Epithelial Appendages: Variations on Top of a Common Theme and Implications in Regeneration

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