Figure 1. Figure summarizes some of the most important epigenetic modifications that occur on DNA, on amino-terminal tails of core histones and on H1, highlighting their relevance for determining that architectural structure of chromatin that makes it competent or not to allow gene expression.

Figure 1

Figure summarizes some of the most important epigenetic modifications that occur on DNA, on amino-terminal tails of core histones and on H1, highlighting their relevance for determining that architectural structure of chromatin that makes it competent or not to allow gene expression. Little red asterisks indicate the presence of 5mC in DNA. M, methyl groups on histones. Ac, acetyl groups on histones. Molecules depicted on top right represent automodifying PARP-1. DB, DNA-binding domain; AM, automodification domain; C, catalytic domain.

From: Parp and Epigenetic Regulation

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