FIGURE 5. Potassium channel families.


Potassium channel families. The potassium channel family has been classified in four subgroups according to their membrane topology. The first and largest group is the voltage-gated potassium channel subtype family with six trans-membrane domains and one pore domain. The second group is the calcium-activated potassium channel subtype family (KCa), which contains six or seven trans-membrane domains and one pore domain. The third group is the inward rectifier subtype family with two trans-membrane domains and one pore domain. The fourth group is the two-pore domain potassium channel subtype family that contains four trans-membrane domains and as its name indicates two pore domains [717]. BKCa: large conductance KCa; IKCa: intermediate conductance KCa; SKCa: small conductance KCa.

From: Chapter 3, Calcium Signaling in Vascular Cells and Cell-to-Cell Communications

Cover of The Endothelium
The Endothelium: Part 1: Multiple Functions of the Endothelial Cells—Focus on Endothelium-Derived Vasoactive Mediators.
Félétou M.
San Rafael (CA): Morgan & Claypool Life Sciences; 2011.
Copyright © 2011 by Morgan & Claypool Life Sciences Publishers.

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