FIGURE 5. Potassium channel families.

FIGURE 5

Potassium channel families. The potassium channel family has been classified in four subgroups according to their membrane topology. The first and largest group is the voltage-gated potassium channel subtype family with six trans-membrane domains and one pore domain. The second group is the calcium-activated potassium channel subtype family (KCa), which contains six or seven trans-membrane domains and one pore domain. The third group is the inward rectifier subtype family with two trans-membrane domains and one pore domain. The fourth group is the two-pore domain potassium channel subtype family that contains four trans-membrane domains and as its name indicates two pore domains [717]. BKCa: large conductance KCa; IKCa: intermediate conductance KCa; SKCa: small conductance KCa.

From: Chapter 3, Calcium Signaling in Vascular Cells and Cell-to-Cell Communications

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The Endothelium: Part 1: Multiple Functions of the Endothelial Cells—Focus on Endothelium-Derived Vasoactive Mediators.
Félétou M.
San Rafael (CA): Morgan & Claypool Life Sciences; 2011.
Copyright © 2011 by Morgan & Claypool Life Sciences Publishers.

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