Evidence Table 1Risk of bias in randomized controlled trials

Author, yearFollowup studiessequence adequately generatedallocation adequately concealedallocated intervention adequately prevented for personnel during the study(ST)allocated intervention adequately prevented for outcome assessors during the study (LT)allocated intervention adequately prevented for personnel during the study(LT)allocated intervention adequately prevented for outcome assessors during the study (LT)incomplete outcome data adequately addressed (ST)incomplete outcome data adequately addressed (LT)reports of the study free of suggestion of selective outcome reportingfree of other problems that could put it at a high risk of biasRoB Score
Ballard, 20061HIbbs, 20072
Walsh, 20103
++++++++++good
Dani, 200640+--+-poor
Fanco-Belgium, 19995++--
+
00++fair
Field, 20056Huddy, 20087-+--------poor
Hascoet, 20058Hamon, 20059++0000++0+fair
Kinsella, 199910++++++++++good
KinsellaM, 200611Watson, 200912+++++++good
Mercier, 2010{#122 62}+++++++0+fair
Schreiber, 200313Mestan, 200514+++++++good
Srisuparp, 200215+00000-+--poor
Su, 200816+0-0-0-0+0poor
Subhedar, 199717Bennett, 200118+0--00+00-poor
Van Meurs, 200519Chock, 200920
Hintz, 200721
+++++++good
Van Meurs, 200722Chock20++++++++++good
KEY
CategoryQuestionYesNoUnclear
Sequence generation:Was the allocation sequence adequately generated?+-0
Allocation concealment:Was the allocation adequately concealed+-0
Blinding of personnel (short-term outcomes)Was knowledge of the allocation intervention adequately prevented for personnel during the study?+-0
Blinding of outcome assessors (short-term outcomes)Was knowledge of the allocated intervention adequately preventes for outcome assessors during the study?+-0
Blinding of personnel long-term outcomes)Was knowledge of the allocation intervention adequately prevented for personnel during the study?+-0
Blinding of outcome assessors Long-term outcomes)Was knowledge of the allocated intervention adequately preventes for outcome assessors during the study?+-0
Incomplete outcome data (short-term)Were incomplete data adequately addressed?+-0
Incomplete outcome data (short-term)Were incomplete data adequately addressed?+-0
Selective outcome reportingAre reports of the study free of suggestion of selective outcome reporting?+-0
Other sources of biasWas the study apparently free of other problems that could put it at high risk of bias?+-0
good = all criteria were present "yes"
fair = greater than or equal to 50% of criteria are present
poor = less than 50% of criteria are present or unclear

From: Appendix E, Evidence Tables

Cover of Inhaled Nitric Oxide in Preterm Infants
Inhaled Nitric Oxide in Preterm Infants.
Evidence Reports/Technology Assessments, No. 195.
Allen MC, Donohue P, Gilmore M, et al.

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