Scheme 2. Synthesis of compound 10.

Scheme 2Synthesis of compound 10

Reagents and conditions: (i) PhB(OH)2, Na2CO3, Pd(PPh3)4, 100 °C, 2 h; (ii) TFA, DMC; (iii) iPrNEt2, 7a, 1,1′-thiocarbonyldimididazole, DCM, MW 150 °C, 10 min; (iv) TFA

From: Identification of Modulators of the N370S Mutant Form of Glucocerebrosidase as a Potential Therapy for Gaucher Disease - Chemotype 2

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

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