Table C-9KQ 2: TPMT status and change in management – risk of bias assessment of included study, part 2

Was there a high loss to follow-up or important differential loss to follow-up between groups?Was treatment adherence assessed?Reviewers’ overall risk of bias assessment for the studyApplicability based on population characteristics and testing methodology
NoYesFair – concealment of allocation is not certain, potential for selection biasLimited applicability because there was just one homozygous carrier in the whole sample of mostly IBD patients

From: Appendix C, Evidence Tables

Cover of Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs
Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs.
Evidence Reports/Technology Assessments, No. 196.
Booth RA, Ansari MT, Tricco AC, et al.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.