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Booth RA, Ansari MT, Tricco AC, et al. Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs. Rockville (MD): Agency for Healthcare Research and Quality (US); 2010 Dec. (Evidence Reports/Technology Assessments, No. 196.)

Cover of Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs

Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs.

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Appendix CEvidence Tables

Additional data are presented here for Key Questions 1b, 1c, 2, 3a, 3b, 3c and 4 Reference list is provided at the end of the document

Key Question 1b. Within and between laboratory precision and reproducibility of enzymatic measurement of TPMT and determination of TPMT allelic polymorphisms

Table C-1. KQ 1b: Precision and reproducibility of TPMT status determinations

Key Question 4. For patients with chronic autoimmune disease, costs of TPMT testing, and treating drug-associated complications

Table C-26. KQ 4: Costs of TPMT testing

Table C-27. KQ 4: Costs of treating azathioprine-associated complications


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