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Smith B, Peterson K, Fu R, et al. Drug Class Review: Drugs for Fibromyalgia: Final Original Report [Internet]. Portland (OR): Oregon Health & Science University; 2011 Apr.

Cover of Drug Class Review: Drugs for Fibromyalgia

Drug Class Review: Drugs for Fibromyalgia: Final Original Report [Internet].

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Evidence Tables

Evidence Table 1. Data abstraction of fibromyalgia trials

Evidence Table 2. Quality assessment of fibromyalgia trials

Evidence Table 3. Data abstraction of systematic reviews

Evidence Table 4. Quality assessment of systematic reviews

Abbreviations used in evidence tables

ACR

American College of Rheumatology

ACT

Active-control trial

AE

Adverse event

AIMS

Arthritis Impact Measurement Scale

ANCOVA

Analysis of covariance

ANOVA

Analysis of variance

ARA

American Rheumatism Association

BAI

Beck Anxiety Index

BDI

Beck Depression Inventory

bid

Twice daily

BMI

Body mass index

BOCF

Baseline Observation Carried Forward

BPI

Brief Pain Inventory

BPI-SF

Brief Pain Inventory-Short Form

CCT

Controlled clinical trial

CGIC

Clinical Global Impression of Change

CGIS

Clinical Global Impression of Severity

CI

Confidence interval

CNS

Central nervous system

CR

Controlled release

CV

Cardiovascular

CVS

Cardiovascular system

d

Day

DB

Double-blind

DEXA

Dual Energy X-ray Absorptiometry

dL

Deciliter

ECG

Electrocardiogram

EEG

Electroencephalogram

EF

Ejection fraction

ER

Extended release

FDA

US Food and Drug Administration

FIQ

Fibromyalgia Impact Questionnaire

FU

Follow-up

g

Gram

GI

Gastrointestinal

GLMM

Generalized Linear Mixed Model

GP

General practitioner

h

Hour

HAD

Hospital Anxiety and Depression scale

HAMD

Hamilton Depression Scale

HAQ

Health Assessment Questionnaire

HDL-C

High density lipoprotein cholesterol

HMO

Health maintenance organization

HR

Hazard ratio

HRQOL

Health-related quality of life

ICD-10

International Classification of Diseases, Tenth Revision

ICD-9

International Classification of Diseases, Ninth Revision

IGF-1

Insulin-like growth factor 1

IR

Immediate release

ITT

Intention-to-treat

L

Liter

LA

Long acting

LDL-C

Low-density lipoprotein cholesterol

LOCF

Last observation carried forward

LS means

Least squares means

LTR

Loss of Therapeutic Response

MADRS

Montgomery Åsberg Depression Rating Scale

MAF

Multidimensional Assessment of Fatigue

MANCOVA

Multivariate analysis of covariance

MASQ

Multiple Ability Self-Report Questionnaire

mcg

Microgram

MCS

Mental Component Summary

MDD

Major Depressive Disorder

MFI

Multidimensional Fatigue Inventory

mg

Milligram

min

Minute

mL

Milliliter

mo

Month

MOS

Medical Outcomes Study

N

Sample size (entire sample)

n

Subgroup sample size

NA

Not applicable

NR

Not reported

NS

Not significant

NSAIDs

Nonsteroidal antiinflammatory drugs

NSD

No significant difference

OC

Observed cases

OR

Odds ratio

P

P value

P

Placebo

PCS

Physical Component Summary

PCT

Placebo-controlled trial

PED

Patient Experience Diary

PGIC

Patient’s Global Impression of Change

PPY

Per person year

PVA

Pain Visual Analog

qd

Once daily

QOL

Quality of life

RA

Rheumatoid arthritis

RCT

Randomized controlled trial

REM

Rapid eye movement

RR

Relative risk

SB

Single-blind

SD

Standard deviation

SE

Standard error

SEM

Standard error of the mean

SF-36

Short-Form 36 Health Survey

SF-MPQ

Short-Form McGill Pain Questionnaire

SIP

Sickness Impact Profile

SMR

Skeletal muscle relaxants

SQ

Subcutaneous

SR

Sustained release

SSRI

Selective Serotonin Reuptake Inhibitor

STAI-S

State-Trait Anxiety Inventory, State-related

TEAE

Treatment-emergent adverse event

tid

Three times daily

VAS

Visual analog scale

vs.

Compared with (versus)

WD

Withdrawal

XR

Extended release

y

Year

Copyright © 2011, Oregon Health & Science University.
Bookshelf ID: NBK55549

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