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National Collaborating Centre for Chronic Conditions (UK). Stroke: National Clinical Guideline for Diagnosis and Initial Management of Acute Stroke and Transient Ischaemic Attack (TIA). London: Royal College of Physicians (UK); 2008. (NICE Clinical Guidelines, No. 68.)

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Stroke: National Clinical Guideline for Diagnosis and Initial Management of Acute Stroke and Transient Ischaemic Attack (TIA).

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14Research recommendations

The following questions were prioritised as key research recommendations by the GDG:

Does the withdrawal of oral liquids or the use of modified (thickened) oral fluids prevent the development of aspiration pneumonia after an acute stroke?

Does modified-release dipyridamole or clopidogrel with aspirin improve outcome compared with aspirin alone when administered early after acute ischaemic stroke?

Should a person who has a stroke or a TIA and is already taking aspirin be offered the same or an increased dose of aspirin after the stroke?

How safe and effective is very early mobilisation delivered by appropriately trained professionals after stroke?

How safe and effective is the early manipulation of blood pressure after stroke?

What is the safety and efficacy of carotid stenting compared with carotid endarterectomy within 2 weeks of TIA or recovered stroke when these procedures are carried out?

Additional research recommendations identified by the group

A randomised trial comparing direct admission to an acute stroke unit versus admission to a medical ward at least while the latter remains standard clinical practice.

Copyright © 2008, Royal College of Physicians of London.

All rights reserved. No part of this publication may be reproduced in any form (including photocopying or storing it in any medium by electronic means and whether or not transiently or incidentally to some other use of this publication) without the written permission of the copyright owner. Applications for the copyright owner’s written permission to reproduce any part of this publication should be addressed to the publisher.

Bookshelf ID: NBK53283
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