FIGURE 16.3. Schematic representation of Drosophila thermosensory neuron firing patterns.

FIGURE 16.3

Schematic representation of Drosophila thermosensory neuron firing patterns. A low-threshold type has spontaneous room temperature activity and increased firing above 29°C and inactivation at 39°C. A high-threshold type activates at approximately 39°C. Temperature-activated firing of both the low-threshold type and high-threshold type of sensory neuron is absent in painless mutant nerves. In wild-type, thermosensory neurons have the largest amplitude spikes, with spontaneous firing at room temperature, and are detectable in painless mutant nerves (bottom trace) but are not activated by high temperature.

From: Chapter 16, Genetics Can Be Painless: Molecular Genetic Analysis of Nociception in Drosophila

Cover of TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades.
Liedtke WB, Heller S, editors.
Boca Raton (FL): CRC Press; 2007.
Copyright © 2007, Taylor & Francis Group, LLC.

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