Table 31.2. Treatment Decisions Based on LDL-Cholesterol

Dietary Therapy
Initiation LevelLDL Goal
Without CHD and with
fewer than 2 risk factors
>160mg/dL<160 mg/dL
Without CHD and with
2 or more risk factors
>130 mg/dL<130 mg/dL
With CHD>100 mg/dL<100 mg/dL
Drug Treatment
Consideration LevelLDL Goal
Without CHD and with
fewer than 2 risk factors
>190mg/dL * <160 mg/dL
Without CHD and with
2 or more risk factors
>160 mg/dL<130 mg/dL
With CHD>130 mg/dL ** <100 mg/dL

* In men under 35 years of age and premenopausal women with LDL-cholestrol levels 190-219 mg/dL, drug therapy should be delayed except in high-risk patients such as those with diabetes.

** In CHD patients with LDL-cholestrol levels 100-129 mg/dL, the physician should exercise clinical judgment in deciding whether to initiate drug treatment.

From: 31, Cholesterol

Cover of Clinician's Handbook of Preventive Services
Clinician's Handbook of Preventive Services. 2nd edition.
US Public Health Service. Office of Disease Prevention and Health Promotion.

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