Table 16.2. True Contraindications and Precautions * for OPV/IPV Vaccination

VaccineTrue Contraindications and PrecautionsNOT Contraindications
(vaccines may be given)
OPVInfection with HIV or a household
contact with HIV

Known altered immunodeficiency

Immunodeficient household contact

Pregnancy
Breast feeding

Current antimicrobial therapy

Diarrhea
IPVAnaphylactic reaction following a previous
dose of IPV or anaphylactic reaction to
neomycin, polymyxin B or streptomycin

Pregnancy
Breast feeding

Current antimicrobial therapy

Diarrhea

* Precautions should be carefully reviewed. Consider the benefits and risks of administering a specific vaccine to a child under the circumstances. If the risks are believed to outweigh the benefits, withhold the immunization; if the benefits are believed to outweigh the risks (eg, during an outbreak or foreign travel), administer the vaccine. It is prudent on theoretical grounds to avoid vaccinating pregnant women. However, if immediate protection against poliomyelitis is needed, OPV is preferred, although IPV may be considered if full immunization can be completed before the anticipated imminent exposure. Pregnancy of a mother is not a contraindication to giving polio vaccine to her child.

Adapted from: Centers for Disease Control and Prevention. General recommendations on immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR. 1994; 43(RR-1): 24-25, and Centers for Disease Control and Prevention. Poliomyelitis prevention in the United States: introduction of a sequential vaccination schedule of inactivated poliovirus vaccine followed by oral poliovirus vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR. 1997; 46 (No. RR-3): 1-25.

From: 16, Poliomyelitis

Cover of Clinician's Handbook of Preventive Services
Clinician's Handbook of Preventive Services. 2nd edition.
US Public Health Service. Office of Disease Prevention and Health Promotion.

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