Use of linkage analysis in two different families with the same autosomal recessive disorder to clarify carrier status of an at-risk sib (arrow). The same set of markers (1,2,3) is used in both families; different possible alleles at each marker are indicated by the letters A-F.


Revised: 2-9-04

Related Terms: haplotype analysis; linkage analysis; polymorphism

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GeneReviews® [Internet].
Pagon RA, Adam MP, Ardinger HH, et al., editors.
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