Table 6.2Decline in renal function in various populations

ReferencePopulationNGFR decline
163Female healthy kidney donors2050.71 ml/min/year
163Male healthy kidney donors1600.46 ml/min/year
163Healthy kidney donors3650.49 ml/min/1.73m2/year
164Healthy kidney donors1410.4 ml/min/year
166Healthy males (cross-sectional)5480.80 ml/min/1.73 m2/year (CrCl)
166Healthy males (longitudinal)2930.90 ml/min/1.73 m2/year. (CrCl)
165Healthy people (cross-sectional)3,7320.4 ml/min/year
158Healthy + renal/urinary tract disease + hypertensive males (cross-sectional)4460.87 ml/min/year (CrCl)
158Healthy males (longitudinal)2540.75 ml/min/year (CrCl)
158Males with renal/urinary tract disease (longitudinal)1181.10 ml/min/year (CrCl)
158Males with hypertension (longitudinal)740.92 ml/min/year (CrCl)
162Total population (PREVEND cohort)6,8942.3 ml/min/1.73m2 (after 4.2 years)
162Adults with macroalbuminuria (PREVEND cohort)867.2 ml/min/1.73m2 (after 4.2 years)
162Adults with impaired renal function (5% lowest CrCl/MDRD GFR, PREVEND cohort)680.2 ml/min/1.73m2 (after 4.2 years)
161Older males with diabetesNot stated2.7 ml/min/1.73 m2/year
161Older males without diabetesNot stated1.4 ml/min/1.73 m2/year
161Older females with diabetesNot stated2.1 ml/min/1.73 m2/year
161Older females without diabetesNot stated0.8 ml/min/1.73 m2/year

From: 6, Defining progression of CKD and the risk factors associated with progression

Cover of Chronic Kidney Disease
Chronic Kidney Disease: National Clinical Guideline for Early Identification and Management in Adults in Primary and Secondary Care.
NICE Clinical Guidelines, No. 73.
National Collaborating Centre for Chronic Conditions (UK).
Copyright © 2008, Royal College of Physicians of London.

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