Figure 5

Figure 5. The SMAD4 gene on chromosome 18q21.2 spans 55 kb and produces an 8.8-kb transcript encoding a protein of 552 amino acids. Arrow indicates the original 4-basepair deletion mutation found in the large Iowa kindred (see text). See Figure 7 for the Iowa kindred pedigree.

From: Juvenile Polyposis

Cover of Cancer Syndromes
Cancer Syndromes [Internet].
Riegert-Johnson DL, Boardman LA, Hefferon T, et al., editors.
Copyright © 2009-, Douglas L Riegert-Johnson.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.