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Figure 22 displays a forest plot of combined lifestyle trials reporting between-group differences in low-density lipoprotein (LDL) cholesterol. Data for the figure are presented alongside the forest plot. In the moderate-intensity (31 to 360 minutes) subgroup (6 trials) the combined unstandardized weighted mean difference was 0.00 (95% CI, −0.13 to 0.12). In the high-intensity (more than 360 minutes) subgroup (4 trials) the combined unstandardized weighted mean difference was −0.10 (95% CI, −0.20 to 0.00). The overall unstandardized weighted mean difference for all 10 combined lifestyle trials was −0.04 (95% CI, −0.13 to 0.05), indicating that there was not a statistically significant effect on LDLcholesterol. There was moderate statistical heterogeneity, both within the moderate-intensity subgroup (chi-square=46.5%; p=0.096) and between the moderate- and high-intensity subgroups (chi-square=54.6%; p=0.019).

Figure 22Meta-Analysis of Combined Lifestyle Trials (KQ2): Low-Density Lipoproteins

From: 3, Results

Cover of Behavioral Counseling to Promote Physical Activity and a Healthful Diet to Prevent Cardiovascular Disease in Adults
Behavioral Counseling to Promote Physical Activity and a Healthful Diet to Prevent Cardiovascular Disease in Adults: Update of the Evidence for the U.S. Preventive Services Task Force [Internet].
Evidence Syntheses, No. 79.
Lin JS, O’Connor E, Whitlock EP, et al.

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