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Figure 21 displays a forest plot of combined lifestyle trials reporting between-group differences in total cholesterol. Data for the figure are presented alongside the forest plot. In the moderate-intensity (31 to 360 minutes) subgroup (7 trials) the combined unstandardized weighted mean difference was −0.05 (95% CI, −0.20 to 0.10). In the high-intensity (more than 360 minutes) subgroup (4 trials) the combined unstandardized weighted mean difference was −0.13 (95% CI, −0.25 to 0.00). The overall unstandardized weighted mean difference for all 11 combined lifestyle trials was −0.07 (95% CI, −0.18 to 0.03), indicating that there was not a statistically significant effect on total cholesterol. There was moderate statistical heterogeneity, both within the moderate-intensity subgroup (chi-square=64.5%; p=0.010) and the high-intensity subgroup (chi-square=50.0%; p=0.112) and between the two subgroups (chi-square=63.5%; p=0.002).

Figure 21Meta-Analysis of Combined Lifestyle Trials (KQ2): Total Cholesterol

From: 3, Results

Cover of Behavioral Counseling to Promote Physical Activity and a Healthful Diet to Prevent Cardiovascular Disease in Adults
Behavioral Counseling to Promote Physical Activity and a Healthful Diet to Prevent Cardiovascular Disease in Adults: Update of the Evidence for the U.S. Preventive Services Task Force [Internet].
Evidence Syntheses, No. 79.
Lin JS, O’Connor E, Whitlock EP, et al.

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