Figure 15 displays a forest plot of healthful diet trials reporting between-group differences in high-density lipoprotein (HDL) cholesterol after low-fat and general heart-healthy dietary counseling. Data for the figure are presented alongside the forest plot. In the moderate-intensity (31 to 360 minutes) subgroup (3 trials) the combined unstandardized weighted mean difference was 0.03 (95% CI, −0.06 to 0.13). In the high-intensity (more than 360 minutes) subgroup (2 trials) the combined unstandardized weighted mean difference was −0.03 (95% CI, −0.07 to 0.01).The overall unstandardized weighted mean difference for all 5 healthful diet trials was −0.01 (95% CI, −0.04 to 0.03), indicating that there was not a statistically significant effect on HDL cholesterol. However, there was some statistical heterogeneity across the subgroups (chi-square=33.8%; p=0.196). There was moderate statistical heterogeneity within the moderate-intensity subgroup (chi-square=42.2%; p=0.177); heterogeneity was not statistically significant across the subgroups (chi-square=17.2%; p=0.305).

Figure 15Meta-Analysis of Healthful Diet Trials, General Counseling (KQ2): High-Density Lipoproteins

From: 3, Results

Cover of Behavioral Counseling to Promote Physical Activity and a Healthful Diet to Prevent Cardiovascular Disease in Adults
Behavioral Counseling to Promote Physical Activity and a Healthful Diet to Prevent Cardiovascular Disease in Adults: Update of the Evidence for the U.S. Preventive Services Task Force [Internet].
Evidence Syntheses, No. 79.
Lin JS, O’Connor E, Whitlock EP, et al.

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