CIDTarget NameIC50/EC50 (nM) [SID, AID]Anti-target Name(s)IC50/EC50 (μM) [SID, AID]SelectivitySecondary Assay(s) Name: IC50/EC50 (nM) [SID, AID]
CID3342390 (sulfonamide)

ML140
KOR
κ-opioid receptor
850 nM IC50
SID-87218794
AID-2285
MOR
μ-opioid receptor

DOR
δ-opioid receptor
>32 μM IC50
SID-87218794
AID-2420

>32 μM IC50
SID-87218794
AID-2357
> 40X (Dx/HCS)
>25X (HCS/HCS)

> 40X (Dx/HCS)
>25X (HCS/HCS)
KOR Transfluor 1310 nM IC50 [SID-87218794, [AID-2348]

MOR Transfluor >32000 nM IC50 [SID-87218794, [AID-2420]

DOR Transfluor >32000 nM IC50 [SID-87218794, AID-2357]

From: Selective KOP Receptor Antagonists: Probe 1

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

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