Table 8Clozapine and olanzapine: Response rates for 3 definitions of response

Author, year, NKane criteria (Percent responders)PANSS >30% (Percent responders)PANSS >40% (Percent responders)
Bitter 2004
N = 140
Clozapine 61Clozapine 64Clozapine 47
Olanzapine 58Olanzapine 63Olanzapine 50
Tollefson 2001
N = 180
Clozapine 35Clozapine 32Clozapine 16
Olanzapine 38Olanzapine 46Olanzapine 27
Pooled relative risk (95% CI)0.99 (0.80 to 1.22)0.87 (0.59 to 1.27)0.80 (0.51 to 1.24)
Q = 0.30 (df = 1)Q = 2.91 (df = 1)Q = 1.83 (df = 1)
P = 0.59P = 0.09P = 0.18

From: Results

Cover of Drug Class Review: Atypical Antipsychotic Drugs
Drug Class Review: Atypical Antipsychotic Drugs: Final Update 3 Report [Internet].
McDonagh M, Peterson K, Carson S, et al.
Portland (OR): Oregon Health & Science University; 2010 Jul.
Copyright © 2010 by Oregon Health & Science University, Portland, Oregon 97239. All rights reserved.

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