Diagnostic accuracy of IgE compared to a DBPCFC for detection of fish allergy

StudyPopulation testedPrevalenceDiagnostic accuracy for fishComments
Positive test on challengeImmediate reactionDelayed reactionCombined immediate & delayedSensitivity (%)Specificity (%)PPV (%)NPV (%)
Sampson 1997167


Related (earlier) publication (including 40 of the children, Sampson 1984168)
196 children and adolescents, aged 0.6–17.9 years with atopic eczema, ‘approximately’ 50% of whom also had asthma and allergic rhinitis.
It is not clear whether all were suspected of having food allergy, but some were based on the comments made regarding use of DB and open food challenges.
(50% to milk, 73% egg, 49% peanut, 28% soya, 22% wheat, 55% fish)

NR=not reported

From: Evidence tables

Cover of Atopic Eczema in Children
Atopic Eczema in Children: Management of Atopic Eczema in Children from Birth up to the Age of 12 Years.
NICE Clinical Guidelines, No. 57.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2007 Dec.
Copyright © 2007, National Collaborating Centre for Women’s and Children’s Health.

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