Table 6.6Symptoms

Pain outcomeReferenceInterventionAssessment timeOutcome/effect size
Exercise vs control/other exercise
Reductions in pain scores (VAS and WOMAC)1 RCT (McCarthy et al. 2004) (N=214)Home + class-based exercise vs home-based exerciseOne year of follow-upVAS: p<0.001
WOMAC: p=0.036
Favours Home + class exercise
Reductions in pain (AIMS2)1 RCT (Eyigor et al. 2004) (N=44)Progressive resistance exercise vs isokinetic exerciseStudy endpoint (6 weeks)p<0.05
Favours resistance exercise
Pain severity (VAS, WOMAC); night pain and pain on standing (Lequesne Index)1 RCT (Eyigor et al. 2004) (N=44)Progressive resistance exercise vs isokinetic exerciseStudy endpoint (6 weeks)NS
Reduction in pain (VAS score)1 RCT (Huang et al. 2003) (N=132)Isotonic exercise vs isokinetic and isometric exerciseOne-year follow-upp<0.05
Favours isotonic exercise
Reductions in intensity and frequency of transfer pain (getting in and out of bed, chair, car etc)1 RCT (Messier et al. 1997) (N=103)Aerobic exercise vs health education control18 months follow-upBoth: p<0.001
Favours exercise
Reductions in intensity and frequency of transfer pain (getting in and out of bed, chair, car etc)1 RCT (Messier et al. 1997) (N=103)Weight training exercise vs health education control18 months follow-upBoth: p=0.04
Favours exercise
Intensity and frequency of ambulation pain1 RCT (Messier et al. 1997) (N=103)Aerobic exercise vs health education control18 months follow-upNS
Intensity and frequency of ambulation pain1 RCT (Messier et al. 1997) (N=103)Weight training exercise vs health education control18 months follow-upNS
Intensity and frequency of ambulation pain1 RCT (Messier et al. 1997) (N=103)Weight training exercise vs aerobic exercise18 months follow-upNS
WOMAC pain1 RCT (Lim 2002) (N=32)Open kinetic chain exercise vs closed kinetic chain exerciseStudy endpoint (6 weeks)NS
Pain scores (AIMS2, VAS, WOMAC)1 RCT (Mangione and McCully 1999) (N=39)High intensity vs low intensity aerobic exerciseStudy endpoint (10 weeks)NS

From: 6, Non-pharmacological management of osteoarthritis

Cover of Osteoarthritis
Osteoarthritis: National Clinical Guideline for Care and Management in Adults.
NICE Clinical Guidelines, No. 59.
National Collaborating Centre for Chronic Conditions (UK).
Copyright © 2008, Royal College of Physicians of London.

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