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Table 75.2Protective effect of neutralizing antibody in limiting extent of neonatal HSV disease

Neutralizing antibody titer (1 week of life) Extent of disease
SEM (n=17) CNS (n=19) Disseminated (n=11)
<1:5 6 (35%) 2 (11%) 8 (73%) P<0.01
1:5 to 1:20 8 (47%) 15 (78%) 3 (27%)
>1:20 3 (18%) 2 (11%) 0 (0%)
a

From Sullender et al. (1987).

From: Chapter 75, Immunotherapy of HSV infections – antibody delivery

Cover of Human Herpesviruses
Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis.
Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors.
Cambridge: Cambridge University Press; 2007.
Copyright © Cambridge University Press 2007.

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