Copyright © Cambridge University Press 2007.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Bookshelf ID: NBK47376PMID: 21348071
Human Herpesviruses
Biology, Therapy, and Immunoprophylaxis
Edited by Ann Arvin,1 Gabriella Campadelli-Fiume,2 Edward Mocarski,3 Patrick S. Moore,4 Bernard Roizman,5 Richard Whitley,6 and Koichi Yamanishi7.
1 Stanford University, CA School of Medicine
2 University of Bologna, Italy
3 Emory University School of Medicine, USA
4 University of Pittsburgh Cancer Institute, PA, USA
5 The University of Chicago, IL, USA
6 University of Alabama at Birmingham, AL, USA
7 Osaka University School of Medicine, Japan
Cambridge: Cambridge University Press; 2007.
ISBN-13: 978-0-521-82714-0
Copyright © Cambridge University Press 2007.
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi’s Sarcoma-associated herpesvirus, cytom-egalovirus, HHV6A, 6B, and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Contents
- Contributors
- Preface
- I. Introduction: definition and classification of the human
herpesvirusesBernard Roizman.
- II.1. Basic virology and viral gene effects on host cell functions:
alphaherpesvirusesGabriella Campadelli-Fiume and Bernard Roizman.
- II.2. Basic virology and viral gene effects on host cell functions:
betaherpesvirusesEdward Mocarski.
- II.3. Basic virology and viral gene effects on host cell functions:
gammaherpesvirusesPatrick S. Moore.
- III.1. Pathogenesis, clinical disease, host response, and epidemiology:
alphaherpes virusesAnn Arvin and Richard Whitley.
- III.2. Pathogenesis, clinical disease, host response, and epidemiology:
alphaherpes viruses VZVAnn Arvin and Richard Whitley.
- III.3. Pathogenesis, clinical disease, host response, and epidemiology:
betaherpesvirusesAnn Arvin and Richard Whitley.
- III.4. HHV-6A, 6B, and 7Ann Arvin and Richard Whitley.
- III.5. Pathogenesis, clinical disease, host response, and epidemiology:
gammaherpesvirusesPatrick S. Moore.
- IV. Non-human primate herpesvirusesAnn Arvin, Patrick S. Moore, and Richard Whitley.
- V. Subversion of adaptive immunityRichard Whitley and Ann Arvin.
- VI. Antiviral therapyAnn Arvin and Richard Whitley.
- VII. Vaccines and immunotherapyAnn Arvin and Koichi Yamanishi.
- VIII. Herpesviruses as therapeutic agentsRichard Whitley and Bernard Roizman.
- Plates
This publication is in copyright. Subject to statutory exceptionand to the provisions of relevant collective licensing agreements,no reproduction of any part may take place withoutthe written permission of Cambridge University Press.
Every effort has been made in preparing this Publication to provide accurate and up-to-date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors and publishers therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this publication. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use.
Cambridge University Press has no responsibility for the persistence or accuracy of URLs for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate.
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Human Herpesviruses
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