Table 15Percent change in osteodensitometric values after administration of dairy products in children consuming low lactose diets (RCTs)

Study SampleOutcomeActive, Mean STDControl, Mean STDMean Difference (95% CI)
Gibbons, 2004102
74
Bone mineral density, total body9.40±8.608.90±9.840.50 (−2.41; 3.41)
Bone mineral density, lumbar spine16.30±16.3416.80±18.78−0.50 (−6.05; 5.05)
Bone mineral density, hip14.00±16.3412.40±17.891.60 (−3.81; 7.01)
Bone mineral density, Trochanter15.80±18.9314.90±19.680.90 (−5.20; 7.00)
Bone mineral density, femoral neck15.40±16.3415.30±15.210.10 (−4.90; 5.10)
Lumbar spine L1-L4 volumetric density54.30±55.9260.50±65.29−6.20 (−25.36; 12.96)
Cadogan, 1997104
44
Bone mineral density, lumbar spine17.90±6.8016.20±6.701.70 (−1.23; 4.63)
Cheng, 2005107
48
Bone mineral density38.10±1.4035.00±1.40 3.10 (2.54; 3.66)
Bone mineral density in femoral neck (g)26.50±1.4022.40±1.50 4.10 (3.52; 4.68)
Bone mineral content total femur (g)36.90±1.6033.60±1.60 3.30 (2.66; 3.94)
Bone mineral density, spine L2–4 (g)52.40±2.2047.00±2.20 5.40 (4.52; 6.28)
Bone cross-sectional area, radius (mm2)26.20±2.0021.30±2.00 4.90 (4.10; 5.70)
Bone mineral content radius (mg/mm)25.90±1.9022.20±2.00 3.70 (2.92; 4.48)
Volumetric bone mineral density, radius (mg/cm3)3.07±1.501.99±1.50 1.08 (0.48; 1.68)
Bone mineral density, tibia (mg/mm)25.20±1.0022.70±1.00 2.50 (2.10; 2.90)
Volumetric bone mineral density, tibia (mg/cm3)8.30±0.607.76±0.60 0.54 (0.30; 0.78)
Lau, 2004101
100
Bone mineral content, total hip24.42±11.4022.77±11.601.65 (−1.39; 4.69)
Bone mineral density, total hip7.28±4.106.34±4.200.94 (−0.16; 2.04)
Bone mineral content, femoral neck10.01±11.4010.64±12.04−0.63 (−3.72; 2.46)
Bone mineral density, femoral neck6.16±4.605.40±4.750.76 (−0.47; 1.99)
Bone mineral content, spine20.88±9.4019.23±9.391.65 (−0.83; 4.13)
Bone mineral density, spine8.05±5.207.01±5.301.04 (−0.35; 2.43)
Bone mineral content, total body17.02±6.5016.88±6.630.14 (−1.59; 1.87)
Bone mineral density, total body3.06±2.602.39±2.650.67 (−0.02; 1.36)
Bone mineral content, total hip25.89±12.0222.77±11.60 3.12 (0.01; 6.23)
Bone mineral density, total hip7.41±4.246.34±4.201.07 (−0.04; 2.18)
Bone mineral content, femoral neck13.16±12.2210.64±12.042.52 (−0.67; 5.71)
Bone mineral density, femoral neck6.48±4.955.40±4.751.08 (−0.20; 2.36)
Bone mineral content, spine21.51±9.7019.23±9.392.28 (−0.23; 4.79)
Bone mineral density, spine8.37±5.457.01±5.301.36 (−0.06; 2.78)
Bone mineral content, total body18.46±6.7716.88±6.631.58 (−0.18; 3.34)
Bone mineral density, total body2.87±2.732.39±2.650.48 (−0.23; 1.19)

Bold- statistically significant differences at 95% confidence level

From: 3, Results

Cover of Lactose Intolerance and Health
Lactose Intolerance and Health.
Evidence Reports/Technology Assessments, No. 192.
Wilt TJ, Shaukat A, Shamliyan T, et al.

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