From: Appendix H, Additional tables for diabetes results and analysis

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Median Reduction in HbA_{1c}
| |||||
---|---|---|---|---|---|

[inter-quartile range] | |||||

N=Number of trials | |||||

Number of QI Strategies * | All Trials | Trials with sample size in lowest quartile | Trials with sample size in lower 2 quartiles | Trials with sample size in upper 2 quartiles | Trials with sample size in highest quartile |

Any number of strategies
| 0.48 | 1.35 | 0.80 | 0.21 | 0.10 |

[0.20, 1.38] | [0.60,1.48] | [0.41, 1.44] | [0.10, 0.60] | [0.10, 0.33] | |

N=38 | N=10 | N=19 | N=19 | N=10 | |

1 strategy only
| 0.00 | -0.20 ^{^} | 0.15 | 0.00 | 0.00 |

[0.0,0.10] | —— | [0.10,0.20] | [0.00,0.11] | [0.00,0.00] | |

N=5 | N=1 | N=2^{§} | N=3 | N=2 | |

≥ 2 strategies
| 0.60 | 1.40 | 1.08 | 0.34 | 0.15 |

[0.30, 1.40] | [0.71,1.50] | [0.47, 1.47] | [0.10, 0.73] | [0.10, 0.40] | |

N= 33 | N=9 | N=17 | N=16 | N=8 | |

≥ 3 strategies
| 0.66 | 1.35 | 1.19 | 0.55 | 0.35 |

[0.33, 1. 40] | [1.15, 1.40] | [0.53, 1.40] | [0.20, 1.18] | [0.17, 0.53] | |

N=22 | N=4 | N=10 | N=12 | N=4 | |

≥ 4 strategies
| 0.6 | 0.71 | 0.59 | 0.6 | 0.50 |

[0.41,1.1] | —— | [0.43,0.99] | [0.4, 1.5] | [0.35,0.55] | |

N=13 | N=1 | N=6 | N=7 | N=3 | |

≥ 5 strategies
| 0.71 | 0.71 | 0.71 | 0.85 | 0.40 |

[0.53,1.29] | —— | [0.59,1.09] | [0.50,1.53] | [0.20,0.60] | |

N=7 | N=1 | N=3 | N=4 | N=2 | |

6 strategies*
| 1.09 | 0.71 | 1.09 | ||

[0.71,1.47] | —— | [0.71,1.47] | |||

N=2 | N=1 | N=2 | N=0 | N=0 |

- *
Under this alternate classification of the QI strategies, Five studies were still single-faceted,

^{1}–^{5}but the median number of strategies increased from two to three and the maximum number of strategies increased from five to six (seen in two comparisons^{6,}^{7}).- ^
All changes were standardized to reflect reductions. Thus, the negative sign here indicates an

*increase*in serum HbA_{1c}- †
When N=2, the numbers in square brackets reflect the results for each of the two studies rather than the inter-quartile range.

From: Appendix H, Additional tables for diabetes results and analysis

Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies (Vol. 2: Diabetes Care).

Technical Reviews, No. 9.2.

Shojania KG, Ranji SR, Shaw LK, et al.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2004 Sep.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.