Table 8

Cardiovascular adverse events among dementia patients – Atypical Antipsychotics Compared to Placebo

Adverse EventsDrug# of studiesPlaceboIntervention GroupsPooled OR95% CINNH95% CI NNH
# adverse eventssample size# adverse eventssample size
Cardiovascular/CVAOlanzapine2223252782.09(0.32, 23.27)NCNC
Cardiovascular/CVARisperidone36550214873.88(1.49, 11.91)31(19, 82)
Cardiovascular –otherOlanzapine45298386783.31(1.27, 10.91)25(16, 60)
Cardiovascular –otherRisperidone42766511010602.33(1.48, 3.78)16(12, 25)

NC = Not calculated

From: 3, Results

Cover of Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics
Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics [Internet].
Comparative Effectiveness Reviews, No. 6.
Shekelle P, Maglione M, Bagley S, et al.

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