Table 47Single-arm studies, time to event outcomes, KQ5, head and neck cancer

StudyTime to Event Outcomes
Nagler et al., 2003
surgery
OutcomeGrpNMed (mos)1 yr2 yr3 yr4 yr5 yrTestpHR (95%CI)Comments
OSIHC+1030LR0.0004
IHC-2672
Khan et al., 2002
surgery+EBRT
OutcomeGrpNMed (mos)1 yr2 yr3 yr4 yr5 yrTestpRR (95%CI)Comments
DFSIHC+ vs. -?UV Cox0.83 (0.29, 2.4)
OSIHC+ vs. -?UV Cox1.4 (0.62, 3.3)
OSFISH disom/-475.843
FISH polysom53.140LR0.15LR test for combined disomic, non-overexpressed+ polysomic
FISH+42.20

Abbreviations: DFS: disease-free survival; LR: log rank; OS: overall survival; UV: univariate;

From: 3, Results and Conclusions

Cover of HER2 Testing to Manage Patients With Breast Cancer or Other Solid Tumors
HER2 Testing to Manage Patients With Breast Cancer or Other Solid Tumors.
Evidence Reports/Technology Assessments, No. 172.
Seidenfeld J, Samson DJ, Rothenberg BM, et al.

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