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Table V-GLung Cancer: Tumor Response and Quality of Life

StudyTumor Response (%)Quality of Life
Krug et al. 2005GrpNCRPRSDPDTestpCommentsScaleDomainF/UGrpnmn±sd
Cappuzzo et al. 2005GrpNCR+PRSDPDTestpCommentsScaleDomainF/UGrpnmn±sd
FISH+2334.8ChiSq0.001
FISH-786.40.08Cox MV adjusted for EGFR mutation HR 0.22 (95% CI: 0.04, 1.21)
GrpNCR+PR+SDPDTestpComments
FISH+2356.5ChiSq0.04
FISH-7833.3
Hirsch et al. 2005GrpNCR+PRSDPDTestpCommentsScaleDomainF/UGrpnmn±sd
FISH+1136%?>.05
FISH-2846%
Pelosi et al. 2005GrpNCRPRSDPDTestpCommentsScaleDomainF/UGrpnmn±sd
Saad et al. 2004GrpNCRPRSDPDTestpCommentsScaleDomainF/UGrpnmn±sd
Langer et al. 2004GrpNResponseTestpCommentsScaleDomainF/UGrpnmn±sd
IHC3+825
IHC2+2317.4
IHC1+2133.3
Cappuzzo et al. 2003GrpNCRPRSDPDTestpCommentsScaleDomainF/UGrpnmn±sd
HER2 2+/3+1513.326.7ChiSq0.126
HER2 0/1+2814.350.0
Koukourakis et al. 1999GrpNCRPRSDPDTestpCommentsScaleDomainF/UGrpnmn±sd
Koukourakis et al. 2000GrpNCRPRSDPDTestpCommentsScaleDomainF/UGrpnmn±sd
Graziano et al. 1998GrpNResponseTestpCommentsScaleDomainF/UGrpnmn±sd
HER2+1030FE0.999
HER2-3633
Pfeiffer et al. 1996GrpNCRPRSDPDTestpCommentsScaleDomainF/UGrpnmn±sd

From: Appendix C. Evidence Data Abstraction Tables

Cover of HER2 Testing to Manage Patients With Breast Cancer or Other Solid Tumors
HER2 Testing to Manage Patients With Breast Cancer or Other Solid Tumors.
Evidence Reports/Technology Assessments, No. 172.
Seidenfeld J, Samson DJ, Rothenberg BM, et al.

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