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Cover of Evidence for the Reaffirmation of the U.S. Preventive Services Task Force Recommendation on Screening for High Blood Pressure

Evidence for the Reaffirmation of the U.S. Preventive Services Task Force Recommendation on Screening for High Blood Pressure

Evidence Syntheses, No. 56

Investigators: , MD, MPH and , DrPH.

Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services, 540 Gaither Road, Rockville, MD 20850
Rockville (MD): Agency for Healthcare Research and Quality (US); .
Report No.: 08-05105-EF-1

Structured Abstract

Background:

High blood pressure is common, and screening is a well-established evidence-based standard of current medical practice.

Purpose:

To perform a literature search for new, substantial evidence on screening for high blood pressure that would inform the reaffirmation of the U.S. Preventive Services Task Force recommendation on screening for high blood pressure.

Data Sources:

The PubMed and Cochrane databases were searched. The searches were limited to English-language articles on studies of adult humans (age >18 years) that were published between 1 October 2001 and 31 March 2006 in core clinical journals.

Study Selection: For the literature on benefits, meta-analyses; systematic reviews; and randomized, controlled trials were included. For harms, meta-analyses; systematic reviews; randomized, controlled trials; cohort studies; case—control studies; and case series of large, multisite databases were included. Two reviewers independently reviewed titles, abstracts, and full articles for inclusion.

Data Extraction:

No new evidence was found on benefits or harms of screening. Two reviewers extracted data from studies on the harms of early treatment, including adverse effects of drug therapy and adverse quality-of-life outcomes.

Data Synthesis:

No new evidence was found for the benefits of screening for high blood pressure. New evidence on the harms of treatment of early hypertension shows that pharmacologic therapy is associated with common side effects; serious adverse events are uncommon.

Limitations:

The nonsystematic search may have missed some smaller studies on the benefits and harms of screening and treatment for high blood pressure.

Conclusions:

No new evidence was found on the benefits of screening. Pharmacotherapy for early hypertension is associated with common side effects.

This report was also published in the Annals of Internal Medicine. Wolff T, Miller T. Evidence for the reaffirmation of the U.S. Preventive Services Task Force recommendation on screening for high blood pressure. Ann Intern Med. 2007 Dec 4; 147:787–791.

Suggested citation:

Wolff T, Miller T. Evidence for the Reaffirmation of the U.S. Preventive Services Task Force Recommendation on Screening for High Blood Pressure. Evidence Synthesis No. 56. AHRQ Publication No. 08-05105-EF-1. Rockville, Maryland: Agency for Healthcare Research and Quality. December 2007.

This report is based on research conducted by the staff of the Agency for Healthcare Research and Quality (AHRQ), Rockville, Maryland.

The findings and conclusions in this document are those of the authors, who are responsible for its content, and do not necessarily represent the views of AHRQ. No statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.

The information in this report is intended to help clinicians, employers, policymakers, and others make informed decisions about the provision of health care services. This report is intended as a reference and not as a substitute for clinical judgment.

This report may be used, in whole or in part, as the basis for the development of clinical practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.

No investigators have any affiliations or financial involvement (e.g., employment, consultancies, honoraria, stock options, expert testimony, grants or patents received or pending, or royalties) that conflict with material presented in this report.

Bookshelf ID: NBK33934PMID: 20722151
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