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Cover of Screening for Human Immunodeficiency Virus

Screening for Human Immunodeficiency Virus

Focused Update of a 2005 Systematic Evidence Review for the U.S. Preventive Services Task Force

Evidence Syntheses, No. 46

Investigators: , MD and , MS.

Oregon Evidence-based Practice Center, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239.
Rockville (MD): Agency for Healthcare Research and Quality (US); .
Report No.: 07-0597-1-EF

Excerpt

This report updates an evidence synthesis commissioned by the U.S. Preventive Services Task Force (USPSTF) and completed in March 2005, on screening for unsuspected human immunodeficiency virus (HIV) using HIV antibody (Ab) tests in non-pregnant adolescents (aged 13 to 18 years old) and adults. This brief update was requested by the USPSTF to determine whether there is sufficient new evidence to justify revision of recommendations based on the 2005 evidence synthesis. A key reason for this update is the release in September 2006 of revised Centers for Disease Control and Prevention (CDC) recommendations advising routine voluntary HIV screening of most U.S. adolescents and adults. The 2005 USPSTF recommendations differ from the revised CDC recommendations in that they do not recommend for or against routine screening non-pregnant adults and adolescents who do not report risk factors and are not in high-prevalence (>1%) or other high-risk settings. Staff at the CDC have indicated that the agency's expanded screening recommendations are based primarily on new evidence as to the effects of HIV screening on transmission risk. This report focuses on new or “breakthrough” evidence that could affect the 2005 USPSTF recommendations regarding routine screening of low- or average-risk adults and adolescents.

Contents

U.S. Department of Health and Human Services, 540 Gaither Road, Rockville, MD 20850. www​.ahrq.gov

This report is based on research conducted by the Oregon Evidence-based Practice Center (EPC), Portland, Oregon under contract to the Agency for Healthcare Research and Quality (AHRQ)1 , Rockville, MD (Contract No. 290-02-0024), Task Order Number 1.

Suggested citation:

Chou, R, Huffman, L, Screening for Human Immunodeficiency Virus: Focused Update of a 2005 Systematic Evidence Review for the U.S. Preventive Services Task Force. Prepared for the Agency for Healthcare Research and Quality by the Oregon Evidence-based Practice Center at the Oregon Health and Science University, Portland, Oregon, under Contract No. 290-02-0024, Task Order Number 1. AHRQ Publication No. 07-0597-EF-1. Rockville, Maryland: Agency for Healthcare Research and Quality. April 2007.

The findings and conclusions in this document are those of the authors, who are responsible for its content, and do not necessarily represent the views of AHRQ. No statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.

The information in this report is intended to help clinicians, employers, policymakers, and others make informed decisions about the provision of health care services. This report is intended as a reference and not as a substitute for clinical judgment.

This report may be used, in whole or in part, as the basis for the development fo clinical practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.

1

U.S. Department of Health and Human Services, 540 Gaither Road, Rockville, MD 20850. www​.ahrq.gov

Bookshelf ID: NBK33475PMID: 20722143
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